Semax

Semax is a synthetic heptapeptide derived from a fragment of adrenocorticotropic hormone (ACTH 4–10), modified to enhance stability and biological activity. It has been studied primarily for its potential neuroprotective, cognitive-supportive, and regulatory effects within the central nervous system.

Semax is believed to influence multiple neurotransmitter systems and neurotrophic pathways involved in learning, memory, and stress adaptation.

In laboratory and clinical research settings, Semax has been investigated for its potential role in:

• Supporting cognitive performance and memory processes

• Enhancing focus and mental clarity

• Modulating brain-derived neurotrophic factor (BDNF) expression

• Supporting neuroprotection under stress conditions

• Influencing dopaminergic and serotonergic signaling pathways

Research suggests that Semax may increase BDNF and other neurotrophic factors involved in neuronal growth, plasticity, and repair. It has also been studied for its potential role in supporting cerebral blood flow and metabolic activity in the brain.

In certain research contexts, Semax has been explored for its potential use in post-ischemic recovery and cognitive support. However, broader large-scale international clinical trials remain limited, and regulatory approval varies by region.

Further research is ongoing to better define its mechanisms, long-term safety profile, and therapeutic potential across neurological and cognitive applications.

For research use only.